Integrating one-dimensional and three-dimensional maps of genomes
نویسندگان
چکیده
منابع مشابه
Integrating one-dimensional and three-dimensional maps of genomes.
Genomes exist in vivo as complex physical structures, and their functional output (i.e. the gene expression profile of a cell) is related to their spatial organization inside the nucleus as well as to local chromatin status. Chromatin modifications and chromosome conformation are distinct in different tissues and cell types, which corresponds closely with the diversity in gene-expression patter...
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Luis A. P. Lozada1 C. X. de Mendon a2 Jorge Stolfi1 1Inst. of Computing, University of Campinas Caixa Postal 6176, 13083-970, Campinas, SP, Brazil flozada,stolfig d .uni amp.br 2Informati s Dept., University of Maring a CEP 87020-900 Blo o 19, Maring a, PR, Brazil xavier din.uem.br Abstra t. A three-dimensional map is a partition of a 3D manifold into topologi al polyhedra. We onsider here the ...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2010
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.051631